Roe K, Shu GL, Draves KE, Giordano D, Pepper M, and Clark EA
Targeting Antigens to CD180 but Not CD40 Programs Immature and Mature B Cell Subsets to Become Efficient APCs Programs Immature and Mature B Cell
Keystone Symposium, Dresden Germany. Targeting antigens to CD180 induces a robust humoral response by activating immature B cells and promoting survival and proliferation of Ag-specific B cells. Kelsey Roe, Geraldine Shu, Kevin E. Draves, Edward A. Clark Department of Immunology, School of Medicine, University of Washington, Seattle, Washington
Giordano D, Draves KE, Young LB, Roe K, Bryan MA, Dresch C, et al. (2017) Protection of mice deficient in mature B cells from West Nile virus infection by passive and active immunization. PLoS Pathog 13(11): e1006743. https://doi.org/10.1371/journal.ppat.1006743
Chaplin J, Chappell CP, and Clark EA (2013)
Targeting antigens to CD180 rapidly induces
antigen-specific IgG, affinity maturation,
and immunological memory.