Scientific Publications and Presentations



Roe K, Shu GL, Draves KE, Giordano D, Pepper M,  and Clark EA

Targeting Antigens to CD180 but Not CD40 Programs Immature and Mature B Cell Subsets to Become Efficient APCs Programs Immature and Mature B Cell


June 2018

Keystone Symposium, Dresden Germany.   Targeting antigens to CD180 induces a robust humoral response by activating immature B cells and promoting survival and proliferation of Ag-specific B cells. Kelsey Roe, Geraldine Shu, Kevin E. Draves, Edward A. Clark Department of Immunology, School of Medicine, University of Washington, Seattle, Washington


November 2017

Giordano D, Draves KE, Young LB, Roe K, Bryan MA, Dresch C, et al. (2017) Protection of mice deficient in mature B cells from West Nile virus infection by passive and active immunization. PLoS Pathog 13(11): e1006743.


Chaplin J, Chappell CP, and Clark EA (2013) 

Targeting antigens to CD180 rapidly induces

antigen-specific IgG, affinity maturation,

and immunological memory. 

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